ERCC1 single nucleotide polymorphism C8092A, but not its expression is associated with survival of esophageal squamous cell carcinoma patients from Fujian province, China.

PLoS One · 2014 · PMC4156356 · PMID 25191856

Europe PMC DOI

hedged sentences

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closest p · 0.8× alpha

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boldest claim

The sentences

a significant trendP = 0.04actually significant

Concerning PFS, no significant association was determined when analyzing all three allelic variations (chi-square = 4.2, P = 0.12), although a significant trend was detected (chi-square = 4.1, P = 0.04).

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showed a trendno p-value reported

Here, when all three allelic combinations were statistically compared, those with the AA genotype showed a trend in reduced overall survival, and when two homozygous allelic combinations (AA vs.

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an observed trendno p-value reported

It must be noted that the association between ERCC1 and survival was an observed trend, and not statistically significant.

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