Although there appeared to be less total Akt in the HG group, this did not reach statistical significance ( P = 0.09), but Akt expression increased in the HG + INS group compared to the HG group ( P < 0.05).
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A physiological increase in insulin suppresses muscle-specific ubiquitin ligase gene activation in fetal sheep with sustained hypoglycemia.
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The sentences
Although there appeared to be less phosphorylated Akt, ERK, and P70S6K in the HG + INS group, these failed to reach statistical significance ( P = 0.21, P = 0.09, P = 0.14, respectively, Fig. 4 ).