Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor knockout mice.

PLoS One · 2014 · PMC4209969 · PMID 25347070

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showed a trendno p-value reported

In contrast, in male ORP8 KO mice hepatic expression of ABCA1 showed a trend towards a decrease in expression on both RNA and on protein levels.

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failed to reach statistical significanceno p-value reported

While there was also a 1.2-fold increase in total cholesterol, this failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.