Cadherin 5 is regulated by corticosteroids and associated with central serous chorioretinopathy.

Hum Mutat · 2014 · PMC4215937 · PMID 24665005

Europe PMC DOI

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highly significantno p-value reported

Consequently, the joint analysis of the two cohorts resulted in highly significant association for most analyzed variants with CSC in males, even after correction for multiple testing (0.05/10 = 0.005).

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did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

In the choriocapillaris, junctions showed a trend toward decreased overlap in prednisolone treated cultures, but this did not reach statistical significance (32% decrease, P = 0.07).

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marginally significantno p-value reported

Of these, association of one SNP each from HSP90 and MAPK1 , and two SNPs from CFH genes were marginally significant ( P ∼0.005–0.02) in one of the two cohorts and in the joint analysis, which could indicate a clinically insignificant finding (Supp.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.