Dysregulated B cell expression of RANKL and OPG correlates with loss of bone mineral density in HIV infection.

PLoS Pathog · 2014 · PMC4231117 · PMID 25393853

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0800

boldest claim

The sentences

fell just short of statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

Conversely, the median concentrations of osteocalcin were 18% lower in HIV-infected individuals, although this difference fell just short of statistical significance (P = 0.06).

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fell just short of significanceP = 0.06so close (0.05 < p ≤ 0.1)

However, in the HIV positive group, B cell OPG was significantly correlated to femur neck Z-score and fell just short of significance for hip density and Z-scores (P = 0.06 for each).

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just short of significancep = 0.08so close (0.05 < p ≤ 0.1)

When analyzed together, we found a significant positive correlation between B cell OPG and femur neck Z-score, and falling just short of significance, for overall hip Z-score (p = 0.08).

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did not reach statistical significanceno p-value reported

Although a lower proportion of activated and exhausted tissue-like memory B cells from the HIV-positive group expressed OPG, this difference did not reach statistical significance.

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failed to reach statistical significanceno p-value reported

Mean hip BMDs were slightly diminished at all sites in HIV-infected groups compared to controls but failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.