One-year eye-to-eye comparison of wavefront-guided versus wavefront-optimized laser in situ keratomileusis in hyperopes.

At all intervals studied, there were also no statistically significant differences between the groups with regard to the frequency that each achieved an SE within ±0.25 D, ±0.50 D, and ±1.00 D of emmetropia (all P >0.05); there was, however, a trend that failed to reach statistical significance favoring approximately a 40% higher frequency of attaining a refraction within ±0.25 D of emmetropia in the WF-guided group at postoperative month 12 (81.8% [48.2–97.7] vs 36.4% [10.9–69.2]; P =0.13) ( Table 3 , Figure 2A and B ).

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In the WF-optimized group, 5% contrast sensitivity showed a statistically significant decrease of almost one Early Treatment Diabetic Retinopathy Study line at 12 months compared to preoperative measurements; 25% contrast sensitivity also decreased by less than one line, but did not reach statistical significance (preoperative vs 12 months: <5% contrast sensitivity, 0.18±0.10 vs 0.26±0.10 logMAR [slightly worse than 20/30 vs slightly worse than 20/35]; <25% contrast sensitivity, 0.19±0.07 vs 0.25±0.14 logMAR [slightly worse than 20/30 vs slightly better than 20/35]; P =0.04, P =0.14, respectively).

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