Unique predictors of mortality in patients with pulmonary arterial hypertension associated with systemic sclerosis in the REVEAL registry.

20 , 21 However, including all variables in the multivariate model without stepwise selection, 6MWD < 165 m was a significant predictor of death in the non-SSc group (HR = 2.03; 95% CI, 1.01-4.12; P = .05), and 6MWD ≥ 440 m showed a trend toward a protective effect in the SSc group (HR = 0.62; 95% CI, 0.33-1.15; P = .13).

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Although there was a strong trend toward higher mRAP in the SSc group, there were no significant differences in hemodynamics or PAH-specific therapies at the time of enrollment in the SSc vs non-SSc groups.

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