Barely Significant
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Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.

PLoS One · 2015 · PMC4295887 · PMID 25590613

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There was a trend of increased M2 cytokines but this did not reach statistical significance because of the low patient number with serial lavages.

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We found, however, only distinct pro-inflammatory cytokines significantly up-regulated such as IL-8 and CXCL1 while the increase in TNF-alpha and IL-1beta levels failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.