Experimentally-derived fibroblast gene signatures identify molecular pathways associated with distinct subsets of systemic sclerosis patients in three independent cohorts.

PLoS One · 2015 · PMC4301872 · PMID 25607805

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1010

boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant

Other inflammatory signals, including S1P and IL-4 were also higher in early disease though these signals did not reach statistical significance (p > 0.05; Table 3 ).

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failed to reach statistical significancep = 0.101not close (p > 0.1)

An equivalently sized 1415 gene signature from the IL-13 treatment showed enrichment in the inflammatory subset, although this correlation failed to reach statistical significance ( p = 0.101).

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