This genetic polymorphism was also found to be associated with the trend of DR progression; but due to smaller sample sizes in the sub grouped cells P values were either marginally significant or statistically non-significant.
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Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population.
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The sentences
We found that SLMAP rs17058639 C > T gene polymorphism might be associated with increased risk of DR in male subjects but in the present study the association did not reach statistical significance.
We performed “trend analysis” and found a significant trend of association between SLMAP rs17058639 CC genotype and diabetic macular edema (DME) suggesting a role as a prognostic marker for DR in T2DM patients (Additional file 1 : Table S4).