Implantable cardioverter-defibrillator therapy in patients with ventricular fibrillation out of hospital cardiac arrest secondary to acute coronary syndrome.

When considering only the cohort who were discharged “neurologically intact” (CPC score <3, n=107), ICD implantation showed a trend towards reduced all‐cause mortality in the multivariable analysis (HR 0.52 [0.25 to 1.05], P =0.07).

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In VF OHCA due to a potentially reversible cause, namely acute myocardial infarct or ischemia, ICD implantation was not statistically significantly associated with reduced all‐cause mortality after adjusting for potential confounders, but showed a trend towards significance.

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When adjusting only for the first principal component of the risk factors a trend towards reduced mortality was seen in ICD recipients (HR 0.56 [0.30 to 1.02], P =0.059), although this did not reach statistical significance ( Table 3 ).

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