Prenatal stress-induced programming of genome-wide promoter DNA methylation in 5-HTT-deficient mice.

Transl Psychiatry · 2014 · PMC4350514 · PMID 25335169

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

showed a trendP =0.066so close (0.05 < p ≤ 0.1)

Interestingly, the methylation pattern at CpG site 12 matched the observed methylation pattern of the array and, in addition, showed a trend toward a 5-Htt × PS interaction effect (two-way ANOVA P =0.066).

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did not reach statistical significanceno p-value reported

The expression changes of proteolipid protein ( myelin ) 1 ( Plp1 ) did not reach statistical significance, although clearly displaying the same expression pattern.

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