Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma.

Clin Epigenetics · 2015 · PMC4357086 · PMID 25767621

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did not reach statistical significanceno p-value reported

For all three miRNAs, the average Dm value for poorly differentiated (grade 3) CRCs exceeded that of well-differentiated (grade 1) tumors regardless of the MMR status, but the grade associations did not reach statistical significance.

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failed to reach statistical significanceno p-value reported

Inverse trends for these miRNAs were also evident in the colorectal and endometrial cancer cell lines and respective normal tissues we investigated, although the trends failed to reach statistical significance.

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