In our current study, we found a trend toward increased granulocytic to monocytic MDSC frequency in renal tumors from obese mice, although this change did not reach statistical significance.
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Obesity triggers enhanced MDSC accumulation in murine renal tumors via elevated local production of CCL2.
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The sentences
Monocytic TI-MDSC from DIO mice showed a trend toward increased suppressive capacity, but this difference was not statistically significant.