Impact of Postoperative Chemoradiotherapy versus Chemotherapy Alone on Recurrence and Survival in Patients with Stage II and III Upper Rectal Cancer: A Propensity Score-Matched Analysis.

PLoS One · 2015 · PMC4406553 · PMID 25902069

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

showed a trendp = 0.066so close (0.05 < p ≤ 0.1)

The CRT group showed a trend towards better 5-year RFS (77.6% vs. 58.8%, p = 0.066) and DMF rates (79.5% vs. 62.8%, p = 0.060) compared with the CTx group.

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did not reach statistical significanceno p-value reported

First, due to the relatively small sample size of patients who received postoperative CRT, despite being one of the largest studies of upper rectal cancer to be reported, the survival benefit of CRT in high-risk patients (n = 61) did not reach statistical significance.

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