Electrocardiographic features of disease progression in arrhythmogenic right ventricular cardiomyopathy/dysplasia.

Association between ECG and TTE findings TWI in inferior leads were significantly associated with major repolarization criteria (p = 0.02), extensive RV involvement (p = 0.04), the presence of TWI in either lateral precordial lead (V4, V5 or V6; p = 0.05), and the presence of definite ARVC/D (p = 0.05), whereas the presence of echocardiographic LV involvement (p = 0.11) did not reach statistical significance.

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Importantly, the percentage of patients with epsilon waves and average QRS duration significantly increased over time, and the increase in the number of precordial leads with TWI showed a tendency towards significance.

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Univariate logistic regression revealed a highly significant incremental association between the absolute number of precordial leads with TWI and TWI in inferior leads (odds ratio 1.45, 95% confidence interval 1.16 - 1.83, p = 0.001).

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