Antibiotics in early life alter the gut microbiome and increase disease incidence in a spontaneous mouse model of autoimmune insulin-dependent diabetes.

Here again, a trend which did not reach statistical significance was found.

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However, both vancomycin-treated male and female mice showed a trend towards more severe islet infiltration than untreated animals at 10 weeks of age, suggesting a similar effect of vancomycin treatment on the differentiation of pathogenic lymphocytes in the two genders.

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