Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.

Moreover, despite differences in the kinetics of the responses among various T reg activation molecules, with the notable exception of CD27, there was a clear trend for circulating T reg from TD volunteers to display increased levels of S .

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Typhi-specific integrin α4β7 expression in the 10–14 and 21–28 days post-challenge time frames; however, these changes did not reach statistical significance.

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