Functional neuroanatomy of auditory scene analysis in Alzheimer's disease.

There was a significant main effect of test type (name detection/segregation detection: beta = −2.82, CI −4.24 to −1.41, p < 0.001) and a strong trend to a main effect of group (beta = −0.88, CI −1.77 to 0.003, p = 0.051).

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The correlation analysis of peak-voxel beta contrast estimates and post-scan behavioural performance in the AD group revealed no significant relation for name identification (left anterior superior temporal gyrus r = −0.23, p = 0.45; right anterior superior temporal gyrus r = 0.22, p = 0.48) but a near-significant trend for segregation processing (right posterior superior temporal gyrus r = −0.56, p = 0.06).

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