a significant trendP = 0.0151
Using Gini coefficient, we also found a significant trend toward a more skewed clonotype distribution (higher values) in SLE compared to HC ( P = 0.0151, Fig. 1 b).
← all excerpts
Longitudinal analysis of peripheral blood T cell receptor diversity in patients with systemic lupus erythematosus by next-generation sequencing.
3
0.0151
0.0151
The sentences
No significant correlation between the overall repertoire diversity and clinical disease activity was observed for most SLE patients with only two of eleven SLE patients showing a decreasing trend in repertoire diversity approaching the flare time point.
The relative proportion of clonally expanded T cells was higher in SLE as compared to HC, although the difference did not reach statistical significance.