Exposure to traffic and lung function in adults: a general population cohort study.

Results We identified a significant dose–response trend between exposure category and FEV 1 (p=0.03) and borderline significant trend for FVC (p=0.06) after adjusting for covariates.

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13 In a multicentre study, living near dense traffic was associated with a lower FEV 1 and FVC in women, while in men only age-adjusted means of FEV 1 were lowered to near significance. 14 In a multicity study, women living near dense traffic had a lower mean FEV 1 and FVC and increased risk of COPD. 15 However, other studies found no associations between living near a road with dense traffic and FEV 1 or other measures of respiratory morbidity. 16 In individuals with obstructive lung disease, high exposure to dense traffic was associated with airway restriction, with a significantly lower FVC than for the low-exposed individuals in the same group.

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For FVC, there was a significant negative association for the medium exposure category and a significant dose–response trend; for FEV 1 , the dose–response trend did not reach statistical significance ( table 4 ).

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The associations followed a dose–response relationship with a near-significant trend for FEV 1 .

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