Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice.

Psychopharmacology (Berl) · 2015 · PMC4480945 · PMID 25716307

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0650

boldest claim

The sentences

highly significantp < 0.001actually significant

ANOVA revealed a highly significant genotype effect for food ( F (2,114) = 31.38, p < 0.001) and water ( F (2,114) = 43.03, p < 0.001) intake (Fig.

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approached significancep = 0.052so close (0.05 < p ≤ 0.1)

For pCort, sex × group × genotype interaction approached significance ( F (4,103) = 2.43, p = 0.052).

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approaching significancep = 0.065so close (0.05 < p ≤ 0.1)

In females, a time × group interaction approaching significance ( F (1,41) = 3.59, p = 0.065) indicated that sucrose preference was decreased in CMS females after BT/CMS re-exposure ( p = 0.025 compared to baseline), whereas no change over time was observed in CTRL females.

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