Naproxcinod shows significant advantages over naproxen in the mdx model of Duchenne Muscular Dystrophy.

Conversely, the lower dose of 10 mg/kg confirmed a slight effect on muscle function which did not reach statistical significance (Fig. 1a and b ), and no effects on muscle structure (Fig. 1c and d ), as already published [ 26 ].

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Naproxen-treated mdx mice also showed a trend of increased fatigability throughout the 4 weeks of running.

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