Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor.

PLoS One · 2015 · PMC4560414 · PMID 26340537

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did not reach statistical significanceno p-value reported

Due to higher background current induced by 3.16mM nicotine in un-injected control and lower nicotine-induced current, the nicotine-induced currents in R205C, R205H, N171S, and N47D mutants did not reach statistical significance when compared to the un-injected control.

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showed a trendno p-value reported

Note that 4BP-TQS also showed a trend to rescue the ACh and nicotine effects on E173K and D197N mutant.

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