Contrasting Effects of Histone Deacetylase Inhibitors on Reward and Aversive Olfactory Memories in the Honey Bee.

Insects · 2014 · PMC4592598 · PMID 26462690

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0740

boldest claim

The sentences

highly significantp = 0.000not a probability at all

In the 10 mM experiment, by chance bees in the PB treatment group performed better during the second training trial than control bees for discrimination learning ( p = 0.048), however in the test there was a highly significant difference in the opposite direction ( p = 0.000), therefore this chance difference does not seem to have had any lasting effect.

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did not reach statistical significancep = 0.061so close (0.05 < p ≤ 0.1)

Treatment with 20 mM NaB significantly impaired aversive memory at test ( p = 0.045), and trended towards impairing discrimination memory though this did not reach statistical significance ( p = 0.061).

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showed a trendp = 0.074so close (0.05 < p ≤ 0.1)

Caffeine-treated bees showed a trend towards increased movement levels ( p = 0.074) and had significantly decreased grooming behaviour ( p = 0.045; Figure 7 ).

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