99 Therefore, larger cohorts of biopsied patients, such as the NASH CRN, Malaysian cohort and the Italian and UK groups have been used in multiple investigations, which needs to be borne in mind when considering effects of marginal significance.
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Systematic review of genetic association studies involving histologically confirmed non-alcoholic fatty liver disease.
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The sentences
Multivariate analysis showed a highly significant association of the G allele with fibrosis in an additive manner, which remained after adjustment for histological parameters of steatosis, inflammation and ballooning, suggesting an independent variable.
Results did not reach statistical significance for allele frequency or histological characteristics.