The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition.

Focusing on four representative protein-coding genes whose expression level is elevated in the rpb1-CTD11 mutant, we found that further loss of TEC1 showed a trend towards reduced mRNA levels, although the effects were small and not statistically significant ( S8A-S8D Fig ) [ 12 ].

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Ty2 retrotransposons had a tendency for modestly increased mRNA levels although this did not reach statistical significance ( Fig 3B ).

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