Linagliptin Limits High Glucose Induced Conversion of Latent to Active TGFß through Interaction with CIM6PR and Limits Renal Tubulointerstitial Fibronectin.

PLoS One · 2015 · PMC4624988 · PMID 26509887

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

Western blot analysis of pSmad 2 expression showed a trend towards increased expression in diabetic mice, which was ameliorated to some extent by linagliptin (P = 0.08)( Fig 4B ).

also in 53,322 other papers

did not reach statistical significanceno p-value reported

Although both linagliptin and telmisartan showed a reduction in diabetic tubular atrophy, this change did not reach statistical significance ( Fig 3 ).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.