3 SNPs were nominally significant with the most statistically significant difference observed for rs514659 in the ABO gene determining the ABO blood group (frequency of the minor allele C in STEMI patients 48.06% and in NSTEMI patients 43.26%; X 2 P = 0.0066), originally reported to be specifically associated with MI in presence of CAD [ 20 ].
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Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population.
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The sentences
Similar to most already published GWAS CAD/MI loci, the effect of rs656843 was consistent in direction but did not reach statistical significance for MI or NSTEMI in the prospective sample.