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Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.

PLoS One · 2015 · PMC4640865 · PMID 26554713

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Gene expression of several neuronal ion channel proteins also tended to increase as NPs matured into neurons ( S3 Fig ), although some of the markers did not reach statistical significance.

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The decrease in the expression of SCN4B (encodes the beta subunit of voltage gated Type IV sodium channel) observed by microarray analysis was also seen as a reduction in L neurons of BPD cases by qRT-PCR, but this finding failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.