Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.

Eur J Clin Pharmacol · 2015 · PMC4643117 · PMID 26387812

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

In addition to an increased occurrence of hypertension, patients with the variant allele in IL8 rs1126647A>T showed a trend towards improved PFS/OS (22 vs 14 months for median PFS and 40 vs 25 months for median OS), although the differences between groups did not reach statistical significance.

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