Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I-III Non-Small Cell Lung Cancer.

Dis Markers · 2015 · PMC4664813 · PMID 26663950

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

failed to reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

Additionally, ERCC1 was found to be associated with shorter survival (HR = 2.08; 95% CI = 0.97–4.44; p = 0.059) but failed to reach statistical significance ( p = 0.059).

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an interesting trendno p-value reported

Even though the sample size of the present study is limited, and thus the study itself is underpowered to detect significant differences between biomarkers expression and OS, our results suggest an interesting trend in survival curves not only for RRM2 but also for most of the biomarkers specifically for ERCC1, but also for BRCA1, p53R2, and TUBB3.

also in 1,783 other papers

showed a trendno p-value reported

Kaplan-Meier analysis showed a trend in shorter OS for patients with RRM2, TS, and ERCC1, BRCA1 overexpressed tumours.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.