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Reduced vagal control of the heart in high-fat diet mice: a potential role of increased butyrylcholinesterase.

Physiol Rep · 2015 · PMC4673638 · PMID 26537347

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showed a trendno p-value reported
In cholinergic function-related proteins in the atria, protein levels of choline transporter and vesicular acetylcholine transporter were not decreased but increased, and type 2 muscarinic receptors showed a trend toward a reduction in HFD mice atria as compared with regular diet (RD) mice controls.

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The protein level of M2AChR exhibited a trend toward a reduction in atria of HFD mice but did not reach statistical significance as compared with RD mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.