A significant trend for decreasing frequency of CC genotype with concomitant increasing frequency of allele T was demonstrated in tested groups categorized with accordance to GFR (controls – normal GFR, GFR category 1–3 ChGN patients – moderately decreased GFR, HD patients – severe GFR deterioration) ( Figure 1 ).
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Association of Retinoid X Receptor Alpha Gene Polymorphism with Clinical Course of Chronic Glomerulonephritis.
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GFR differences did not reach statistical significance.