In line with this notion, we found at least a strong trend towards an inferior prognosis for HER2 and/or MYC -amplified cancers with co-deletion of PTEN as compared to tumors harboring only one of these alterations.
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The sentences
These analyses suggested an inferior prognosis in cancers harboring PTEN deletions with co-amplifications of HER2 , MYC , or CCND1 as compared to those without co-amplification, but the differences did not reach statistical significance.