Two metabolites, 2-methylhippuric acid and 5-acetylamino-6-amino-3-methyluracil, were markedly increased in COPD smokers compared to healthy non-smokers, and also showed a trend of increase in comparison with healthy smokers, with P values approaching significance.
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Serum Metabolite Biomarkers Discriminate Healthy Smokers from COPD Smokers.
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