After single-dose pretreatment, clomipramine also tended to increase the levels of TGF-1β in this model of inflammation, but the results did not reach statistical significance.
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Study on anti-inflammatory and immunomodulatory effects of clomipramine in carrageenan- and lipopolysaccharide-induced rat models of inflammation.
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The sentences
Clomipramine also tends to increase IL-10 production in the carrageenan model of inflammation but this effect failed to reach statistical significance.