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Study on anti-inflammatory and immunomodulatory effects of clomipramine in carrageenan- and lipopolysaccharide-induced rat models of inflammation.

Biotechnol Biotechnol Equip · 2014 · PMC4684052 · PMID 26740765

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After single-dose pretreatment, clomipramine also tended to increase the levels of TGF-1β in this model of inflammation, but the results did not reach statistical significance.

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Clomipramine also tends to increase IL-10 production in the carrageenan model of inflammation but this effect failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.