Associations of Polymorphisms in MTHFR Gene with the Risk of Age-Related Cataract in Chinese Han Population: A Genotype-Phenotype Analysis.

PLoS One · 2015 · PMC4686960 · PMID 26689687

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nominally significantno p-value reported

However, only haplotype "C-A-T-C" showed a nominally significant association with PSC ARC risk.

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a significant trendno p-value reported

To further assess the joint effect of SNPs rs9651118 and rs1801133 on ARC risk, a combination analysis of these two variants was carried out, and the results indicated that there was a significant trend of increasing ARC risk with increasing number of unfavorable genotypes, reinforcing the results of haplotype analyses.

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