Chronic Exposure to Androgenic-Anabolic Steroids Exacerbates Axonal Injury and Microgliosis in the CHIMERA Mouse Model of Repetitive Concussion.

PLoS One · 2016 · PMC4718534 · PMID 26784694

Europe PMC DOI

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0.2170

closest p · 4.3× alpha

0.2170

boldest claim

The sentences

did not reach statistical significancep = 0.217not close (p > 0.1)

A detailed analysis of individual NSS tasks revealed that 25% of mice in the AAS-rTBI group failed on the 3 cm wide beam walk test (the easiest among 1 cm, 2 cm, and 3 cm wide beam walk tasks) at 1 h post-rTBI, whereas all mice in the VH-rTBI group successfully completed the same task, albeit this finding did not reach statistical significance ( S1 Fig , Fisher’s exact test, p = 0.217).

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showed a trendno p-value reported

AAS treatment did not significantly exacerbate NSS scores in injured mice (Treatment effect: p = 0.352), although we noted that AAS-treated injured mice showed a trend toward higher NSS values over VH controls from 1 h to 2 d post-rTBI.

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