Gentamicin increased the early expression of this cytokine by 2.3-fold in WT mice and by 3.6-fold in STAT1 −/− mice; however, this difference did not reach statistical significance.
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Loss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors.
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The sentences
However, these differences failed to reach statistical significance.
On the other hand, although gentamicin affected the expression of TNF- α and IL-6 in STAT1 −/− explants, this failed to reach significance.