Although the low mutation rate limits the power of mutation signature analyses, there was a clear trend towards C > T/G > A transitions across the tumour cohort (Figure 2B ), with an enrichment in the context of NpCpG, with the exception of TpCpG (Figure 2C ).
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Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes.
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There was a trend for these cases to have either a BRAF mutation (13/24, 58%, p = 0.1744, FET) or an ERBB2 mutation (3/3, p = 0.0526, FET; Supplementary Table S6 ), but this did not reach statistical significance.