There was a clear trend towards significance in the association between high SERPINE1 expression and poor patient survival (HR 1.78, 95%CI 0.98–3.23, p = 0.057), however the differences observed among groups, did not reach statistical significance in the multivariate analysis.
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Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients.
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