In addition, compared to SCr, there was a clear trend towards a better AUC-ROC for UCHI3L1, especially when diagnosing AKI stage ≥2 based on SCr or UO within 12 h after enrollment.
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Urinary chitinase 3-like protein 1 for early diagnosis of acute kidney injury: a prospective cohort study in adult critically ill patients.
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The sentences
The general time–concentration profile of UCHI3L1 showed a trend for increasing concentrations from 24 h before, towards diagnosis of the first episode of AKI SCr/UO stage ≥2 (reference time 0 h; Fig. 3 ).