Efficacy and Safety of Novel Agent-Based Therapies for Multiple Myeloma: A Meta-Analysis.

Biomed Res Int · 2016 · PMC4753325 · PMID 26949704

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a strong trendno p-value reported

Compared with non-bortezomib-based induction, a strong trend toward improved OS was observed with bortezomib-based induction.

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did not reach statistical significanceno p-value reported

Similar results could be seen in the subgroup of thalidomide-based regimens without ASCT, but they did not reach statistical significance in thalidomide-based regimens with ASCT or lenalidomide-based regimens without ASCT, which might be attributed to the small sample size of included studies in these two subgroups and short follow-up periods [ 25 – 28 , 31 , 32 ].

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