Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites.

Clin Epigenetics · 2016 · PMC4774089 · PMID 26937257

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.1960

boldest claim

The sentences

showed a trendp = 0.051so close (0.05 < p ≤ 0.1)

However, patients positive for either or both SEPT9 and SHOX2 methylation showed a trend towards worse prognosis compared to methylation-negative patients, particularly when analyzing the cellular fraction ( p = 0.051) (Fig. 3a ) although statistical significance was not reached.

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did not reach statistical significancep = 0.196not close (p > 0.1)

2b , p = 0.034) while SHOX2 did not reach statistical significance (Fig. 2b , p = 0.196).

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