Barely Significant
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Different definitions of CpG island methylator phenotype and outcomes of colorectal cancer: a systematic review.

Clin Epigenetics · 2016 · PMC4776403 · PMID 26941852

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showed a trendno p-value reported
Again, the majority of studies showed a trend towards reduced survival which was though not consistent and often not statistically significant.

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Most of the studies reported poorer outcome for CIMP+ patients compared with CIMP− patients, but studies often failed to reach statistical significance due to an insufficient sample size.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.