Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility.

PLoS One · 2016 · PMC4780760 · PMID 26950301

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did not reach statistical significanceno p-value reported

Being nulliparous up to ten years prior to symptom onset and obesity were independent risk factors for MS/CIS although the latter did not reach statistical significance ( Table 4 ).

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showed a trendno p-value reported

Neither we, nor any of the previous studies that also showed a trend towards increased risk of MS with COC use[ 2 , 3 ] addressed this issue.

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