Impact of Persistent Cytomegalovirus Infection on Dynamic Changes in Human Immune System Profile.

Collectively, after a period of about 5 years, in spite of a common apparently erratic variability, non-parametric paired comparison of the two time points showed a significant trend to increase (p<0.05) in anti-HCMV IgG and CD8+ anti-pp65 responses ( Fig 2C and 2E ).

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Finally, the counts of lymphocytes and white blood cells showed a slight trend to diminution, but the final effect with this limited number of subjects did not reach statistical significance ( Fig 4C ).

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