An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.

PLoS One · 2016 · PMC4811554 · PMID 27023444

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did not reach statistical significanceno p-value reported

DS-01 immunization did result in an increase in IL-1 levels in the brain of both the 2N and the Ts65Dn mice, but the changes did not reach statistical significance.

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failed to reach statistical significanceno p-value reported

Relative to vehicle, there was a decrease in the levels of Aβ in DS-01-treated Ts65Dn mice, but the reductions failed to reach statistical significance.

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