α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology.

J Neuroinflammation · 2016 · PMC4825077 · PMID 27055651

Europe PMC DOI

hedged sentences

0.0419

closest p · 0.8× alpha

0.0800

boldest claim

The sentences

a clear trendp = 0.0419actually significant

All immunizations tend to increase Foxp3 levels compared to naive, but only low-dose α-syn showed a clear trend to its up-regulation as compared to naive (Fisher’s LSD, p = 0.0419), so the effect was probably due to the adjuvant (Fig 4b ).

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showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

Vaccination with Nα-syn was the only strategy that showed a trend to induce RORγt protein as compare to naive ( p = 0.08, Fisher’s LSD).

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